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STEMCELL Technologies IBMX, Size: 100 mg
Supplier: STEMCELL Technologies 72762
Inhibit cyclic nucleotide phosphodiesterases with IBMX. This cAMP pathway activator induces neural differentiation from human umbilical cord blood-derived mesenchymal stem cells (Tio et al. PLoS One, 2010). When used together with fibroblast growth factor (FGF) 1, dopamine, 12-O-tetradecanoylphorbol-13-acetate (TPA), and forskolin, IBMX induces the expression of tyrosine hydroxylase in neurons derived from the human NT2 cell line (Iacovitti et al. Brain Res, 2001). When used with other small molecules, it also induces the adipogenic differentiation of unrestricted somatic stem cells (USSCs), a CD45-negative population of stem cells isolated from human cord blood (Kögler et al. J Exp Med, 2004; Pittenger et al. Science, 1999). IBMX is supplied as a crystalline solid with ≥98% purity; Molecular weight 222.3 g/mol; CAS Number 28822-58-4. Visit STEMCELL.com for more information and related products.
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