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Cayman Chemical -Ibuprofen-d3 50mg

Supplier: Cayman Chemical 1825550 MG

An irreversible dual inhibitor of EGFR and HER2 (IC50s 34 and 33 nM respectively) inhibits proliferation of A431 SK-BR-3 and SW620 cancer cell lines (IC50s 120 2.5 and 511 nM respectively) suppresses EGFR autophosphorylation and phosphorylation of the downstream effectors AKT and ERK in NCI-H1650 and NCI-H1650(G7) cells inhibits tumor growth in BT474 A431 and SUM190 mouse xenograft models (10 mg/kg)
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