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Medchemexpress LLC Ibutilide (fumarate) | 122647-32-9 | 99.7% | 5 MG
Supplier: Medchemexpress LLC HYB03875MG
Ibutilide fumarate (U70226E) is an action potential-prolonging antiarrhythmic agent. It acts as a potent blocker of the rapidly activating delayed rectifier K⁺ current (IKr) in AT-1 cells. This compound is intended for research use only.
- Potent IKr blocker with an EC50 value of 20 nM in AT-1 cells.
- Blocks IKr in cells expressing HERG+MDR1*1 to the same extent as HERG alone.
- Prolongs cardiac repolarization in vitro and in vivo.
- Appears as a white to off-white solid.
- Recommended storage for solid: 4°C, sealed, away from moisture.
- Recommended storage in solvent: -80°C for 6 months, or -20°C for 1 month.
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