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Medchemexpress LLC ICA-105665 (PF-04895162) | 2694728-63-5 | 99.9% | 355.34 | C19H15F2N3O2 | 25MG
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Supplier:  Medchemexpress LLC HY12546925MG

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ICA-105665 is an orally active small-molecule opener of neuronal Kv7 potassium channels (Kv7.2/7.3 and Kv7.3/7.5) used in research. It penetrates the blood-brain barrier, exhibits antiseizure activity, and has reported effects on liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 311 μM). The compound is supplied as a high-purity white to off-white powder suitable for in vitro and in vivo studies.

  • Cas registry number: 2694728-63-5.
  • Mechanism of action: opens Kv7.2/7.3 and Kv7.3/7.5 potassium channels.
  • Chemical formula: C19H15F2N3O2.
  • Molecular weight: 355.34 g/mol.
  • Purity: 99.9% (rounded).
  • Appearance and form: white to off-white powder.
  • Solubility: soluble in DMSO at 250 mg/mL; ultrasonic assistance recommended.
  • Storage: store powder at -20°C for long-term stability; store solutions at -80°C for short-term use.

Catalog No. 50-002-35692


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