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Medchemexpress LLC Icapamespib hydrochloride | 2267287-26-1 | 98.74% | 599.32 | 25 MG
Supplier: Medchemexpress LLC 25MGHY137441A
Icapamespib hydrochloride is a selective, orally active inhibitor of Epichaperomes assembled by HSP90 with slow dissociation kinetics. It can cross the blood-brain barrier (BBB) and induce epichaperome disassembly by non-covalently binding to HSP90, restoring the normal protein-protein interaction network. It is used in research for neurodegenerative diseases like Alzheimer's and cancers such as glioblastoma and metastatic breast cancer.
- Selective, orally active inhibitor of epichaperomes
- Crosses the blood-brain barrier (BBB)
- Induces epichaperome disassembly
- Restores normal protein-protein interaction networks
- Reduces neurotoxic protein aggregation
- Reduces tumor cell survival signals
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