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Medchemexpress LLC Icatibant (acetate) | 138614-30-9 | 99.9% | 1364.57 | 5 ML
Supplier: Medchemexpress LLC HY10889650MG
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of the bradykinin B2 receptor, with an IC50 of 1.07 nM and a Ki of 0.798 nM. It is intended for research use only. In in vivo studies, Icatibant has been shown to potentiate angiotensin III and Lys-des-Arg9-bradykinin. Animal studies also demonstrated a significant preventive effect on shortening of the large intestine.
- Potent and specific peptide antagonist of bradykinin B2 receptor
- IC50 of 1.07 nM and Ki of 0.798 nM
- Potentiates angiotensin III and Lys-des-Arg9-bradykinin in vivo
- Significant preventive effect on shortening of the large intestine in animal models
- White to off-white solid appearance
- Soluble in H2O and DMSO at 100 mg/mL
- Intended for research use only
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