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Cayman Chemical ICEC0942hydrochlorIde 10mg

Supplier: Cayman Chemical 3099710 MG
A Cdk7 inhibitor (IC50 = 0.04 µM); selective for Cdk7 over Cdk1, -2, -4, -5, -6, and -9 (IC50s = 1.8, 0.62, 49, 9.4, 34, and 1.2 µM, respectively); induces cell cycle arrest at the G2/M phase and apoptosis in HCT116 cells; reduces tumor growth in MCF-7 and HCT116 mouse xenograft models at 100 mg/kg
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