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Apexbio Technology LLC ICG 001, 847591-62-2, MFCD12196918, 5 mg

Supplier: Apexbio Technology LLC A82175

MF: C33H32N4O4, MW: 548.63, Solubility: 27.4315mg/mL in DMSO, 35.47 mg/mL in EtOH with ultrasonic,insoluble in H2O. ICG001 is a small molecule inhibitor that targets Wnt/beta-catenin pathway. It inhibits TCF/beta-catenin mediated transcription by competing with beta-catenin for CBP (CREB binding protein) but not p300 binding with an IC50 of 3 uM. It can be used to specifically evaluate the role of CBP/beta-catenin association on WNT signaling and cell physiology.
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