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Medchemexpress LLC Iclepertin | 1421936-85-7 | 512.42 | 50 MG
Supplier: Medchemexpress LLC HY13893550MG
Iclepertin (BI-425809) is a potent, selective, and orally active glycine transporter 1 (GlyT1) inhibitor. It is inactive against GlyT2 and is used for research into Alzheimer's disease and schizophrenia. It inhibits GlyT1 in rat primary neurons and human SK-N-MC cells, and a single oral administration has shown to increase glycine CSF levels in rats.
- Potent, selective, and orally active glycine transporter 1 (GlyT1) inhibitor
- Inactive against GlyT2
- Used for Alzheimer's disease research
- Used for schizophrenia research
- Increases glycine cerebrospinal fluid (CSF) levels
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