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Medchemexpress LLC Iclepertin | 1421936-85-7 | 99.9% | 512.42 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY138935100MG

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Iclepertin is a potent, selective, and orally active glycine transporter 1 (GlyT1) inhibitor. It is inactive against GlyT2 and can be used for Alzheimer's disease and schizophrenia research.

  • Appearance: Solid, white to off-white
  • Inhibits GlyT1 with IC50 values of 5.2 nM in rat primary neurons and 5.0 nM in human SK-N-MC cells
  • Single oral administration induces a dose-dependent increase of glycine cerebrospinal fluid (CSF) levels
  • Related to neurological disease areas including membrane transporter/ion channel, neuronal signaling, and GlyT

Catalog No. 50-003-51923


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