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Medchemexpress LLC Icotinib hydrochloride | 1204313-51-8 | C22H22ClN3O4 | 10 MM 1 ML
Supplier: Medchemexpress LLC HY1516410MM/1ML
Icotinib Hydrochloride is a potent, CNS-penetrant, and specific Epidermal Growth Factor Receptor (EGFR) inhibitor. It is effective against various mutant forms of EGFR and functions as a click chemistry reagent due to its Alkyne group, enabling copper-catalyzed azide-alkyne cycloaddition with Azide groups. This compound inhibits the proliferation of several cancer cell lines and demonstrates dose-dependent antitumor effects in animal models.
- Potent and specific EGFR inhibitor
- Effective against mutant EGFR forms
- Functions as a click chemistry reagent
- Inhibits kinase activity and tumor cell proliferation
- Exhibits dose-dependent antitumor effects in vivo
- Well-tolerated in animal studies
- Investigated in clinical trials for Non-Small Cell Lung Cancer and other conditions
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