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Enzo Life Sciences ICRF-193 (1mg). CAS: 21416-68-2
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Supplier:  Enzo Life Sciences BMLGR3320001

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A topoisomerase II inhibitor that does not cause DNA damage. Induces apoptosis in several cell lines including K562 and Molt-4 cells. Induces a G2 checkpoint that is associated with an ATR-dependent inhibition of polo-like kinase 1 (plk1) activity and a decrease in cyclin B1 phosphorylation. Alternative name: Meso-4,4'-(3,2-butanediyl)-bis(2,6-piperazinedione). Purity: ≥95% (HPLC). Solubility: Soluble in DMSO (4mg/ml). Long Term Storage: -20°C.

Catalog No. 50-201-0986


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