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Medchemexpress LLC Idarubicin hydrochloride | 57852-57-0 | 99.9% | 533.95 | 1 MG
Supplier: Medchemexpress LLC HY173811MG
Idarubicin hydrochloride is an anthracycline antileukemic agent. It inhibits topoisomerase II, interfering with DNA replication and RNA transcription. It also inhibits the growth of bacteria and yeasts.
- Inhibits topoisomerase II
- Interferes with DNA replication and RNA transcription
- Inhibits the growth of bacteria and yeasts
- Greater cytotoxicity than daunorubicin or doxorubicin in various in vitro systems
- About 57.5-fold and 25-fold more active than doxorubicin and epirubicin, respectively
- Produces a concentration-dependent reduction in cell growth with an IC50 value of approximately 0.01 μM
- Produces a concentration-dependent inhibition of DNA synthesis
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