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Medchemexpress LLC Idarubicin hydrochloride | 57852-57-0 | 99.9% | 533.95 | 100 MG
Supplier: Medchemexpress LLC HY17381100MG
Idarubicin hydrochloride is an anthracycline antileukemic agent that inhibits topoisomerase II, interfering with DNA replication and RNA transcription. It also inhibits the growth of bacteria and yeasts. This agent has demonstrated greater cytotoxicity than daunorubicin or doxorubicin in various in vitro systems, attributed to a better ability to induce topoisomerase II-mediated DNA breaks.
- Inhibits topoisomerase II, interfering with DNA replication and RNA transcription
- Inhibits the growth of bacteria and yeasts
- Greater cytotoxicity than daunorubicin or doxorubicin
- Induces topoisomerase II-mediated DNA breaks
- Produces concentration-dependent reduction in cell growth
- Inhibits DNA synthesis
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