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Abcam IDE 2, endoderm formation inducer, 1MG
Supplier: Abcam AB1452231MG
MW 240.3 Da, Purity >98%. Cell-permeable definitive endoderm formation inducer (EC₅₀ = 223 nM, induction of Sox17 expression in ESCs) similar to IDE 1 (ab145222). Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
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