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AdipoGen IDO1 human pAb
SDP

Supplier:  AdipoGen AG25A0029C100

Encompass_Preferred

Polyclonal Antibody. Recognizes human IDO. Detects a band of ~45kDa by Western blot. Source Rabbit. Applications ELISA, FACS, ICC, WB. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic NOD mice, and as a protective negative regulator in autoimmune disorders.

Catalog No. 50-256-3283


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