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Genscript Corporation iFluor647-Protein L
Supplier: Genscript Corporation M00922500
Protein L is a cell surface protein from Peptostreptoccocus magnus that binds to the variable light chains (kappa chain) of immunoglobulins without interfering with antigen binding In contrast to IgG-binding proteins such as protein A and protein G which bind to the Fc region of immunoglobulins protein L can be used for the detection and purification of mammalian kappa light chain antibodies of all classes Since no part of the heavy chain is involved in the binding interaction Protein L binds a wider range of antibody classes than Protein A or G Protein L binds to representatives of all antibody classes including IgG IgM IgA IgE and IgD Single chain variable fragments (scFv) and Fab fragments also bind to Protein L
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