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Medchemexpress LLC IFN-alpha/beta R2 H 2ug

Supplier: Medchemexpress LLC HYP726132UG
IFN-alpha/beta R2 one of the subunit of IFN- / receptor is a type I IFN receptor IFN-alpha/beta R2 forms the heterodimeric receptor with IFNAR1 and binds to type I IFNs[1] IFN-alpha/beta R2 also interacts with JAK1 and leads to tyrosine phosphorylation of the IFNARs and STAT proteins[2] Upon activation by these IFNs IFNAR1 and IFN-alpha/beta R2 undergo a conformational change to promote a cascade of downstream signaling events including the phosphorylation of Tyk2 and JAK1 STAT1 and STAT2[3] IFN-alpha/beta R2 Protein Human (HEK293 His) is a recombinant human IFN-alpha/beta R2 (I27-K243) with C-terminal 6 His tag which is produced in HEK293 cells
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