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Genscript Corporation Antibody Protein Proteins Proteins 500 UG 1/EA
Supplier: Genscript Corporation Z02916500
Sharing 41% sequence identity with human Interferon gamma (hIFN--gamma) mouse IFN gamma (mIFN--gamma)is a macrophage-activating factor.The active form of IFN--gamma is an antiparallel dimer that sets off IFN--gamma/JAK/STAT pathway. IFN--gamma signaling does diverse biological functions primarily related to host defense and immune regulation including antiviral and antibacterial defense apoptosis inflammation and innate and acquired immunity.While IFN--gamma–induced inflammatory cascade summons a variety of immune-related cell types such as macrophages natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) IFN--gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in avariety of cancers.
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