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Medchemexpress LLC IFN-gamma R1/CD119 2ug

Supplier: Medchemexpress LLC HYP726112UG
IFN-gamma R1 (CD119) one of the subunit of IFN-gamma receptor is a receptor for IFN-gamma IFN-gamma R1 forms the functional receptor with IFN-gamma R2 Upon binding with IFN-gamma IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1] Then JAK1 and JAK2 are phosphorylated and activated and STAT1 is recruited to the receptor complex Phosphorylated STAT1 translocates to the nucleus where it regulates the expression of IFN-responsive genes (e g CD54)[2] IFN-gamma R1/CD119 Protein Mouse (HEK293 His) is a recombinant mouse IFN-gamma R1 with C-terminal 6 His tag which is produced in HEK293 cells
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