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Apexbio Technology LLC Ifosfamide 3778-73-2 10mM (in 1mL DMSO)
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Supplier:  Apexbio Technology LLC A20975.1

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Ifosfamide (CAS 3778-73-2) is an oxazaphosphorine-type alkylating agent structurally analogous to cyclophosphamide As a prodrug it undergoes hepatic activation via cytochrome P450-mediated hydroxylation generating reactive metabolites that form crosslinks within the DNA double strands This alkylation induces DNA damage subsequently inhibiting cell proliferation and promoting apoptosis in rapidly dividing cells Due to these cytostatic and cytotoxic properties Ifosfamide is widely evaluated in oncology research contexts particularly for various hematological malignancies and solid tumors

Catalog No. 50-000-63488


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