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Medchemexpress LLC IGF-I R Human His 100ug
Supplier: Medchemexpress LLC HYP72256100UG
IGF-I receptor (IGF1R) mediates insulin-like growth factor effects binding strongly to IGF1 Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways influencing cell survival protein synthesis and proliferation IGF1R also signals through JAK/STAT inhibiting JNK activation Hybrid receptors show variable binding to IGF1 and insulin IGF-I R Protein Human (His) is the recombinant human-derived IGF-I R protein expressed by E coli with N-6 His labeled tag
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