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AdipoGen IGFLR1 hFc h rec
Supplier: AdipoGen AG40B0087C050
Protein. Human IGFLR1 aa 23-154 is fused at the C-terminus to the Fc portion of human IgG1. Source HEK 293 cells. Endotoxin content <0.05EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS. Binds to its ligand IGFL3 human Prod. No. AG-40B-0090 http//www.adipogen.com/ag-40b-0090/igfl3-human-rec.html in the subnanomolar range < 1ng /ml. Purity >95% SDS-PAGE. Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans IGFL1 to 4 and one in mice mIGFL. mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 formerly TMEM-149. Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family.
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