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Sigma Aldrich Fine Chemicals Biosciences IgG from rat serum reagent50MG

Supplier:  Sigma Aldrich Fine Chemicals Biosciences I413150MG

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IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids Immunoglobins have two heavy (H) and two light (L) chains linked by disulphide linkages. Each light chain comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. The four classes of IgG can be IgG1 IgG2 IgG3 and IgG4. IgG antibody provides protection from infections caused by bacteria fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. Rat IgG is purified from pooled normal rat serum by fractionation and ion-exchange chromatography.

Catalog No. 50-290-4236


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