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Cayman Chemical IgG4humn ELISA Stndard 1ea
SDP

Supplier:  Cayman Chemical 4009241 EA

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An EP1 receptor antagonist (Kis 0.6 and 1.7 nM for human and mouse receptors respectively expressed in CHO cells) is selective for EP1 over EP2 EP3 and EP4 (Kis 1000 67 and 1000 nM respectively for mouse receptors expressed in CHO cells) inhibits PGE2-induced increases in intracellular calcium concentrations in cells expressing human or mouse EP1 (EC50s 50 and 210 nM respectively) reduces the incidence of squamous cell carcinoma and severe dysplasia induced by 4-nitroquinoline 1-oxide in a rat model of tongue carcinogenesis at 400 and 800 ppm in the diet

Catalog No. 50-294-3048


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