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Medchemexpress LLC IK1 inhibitor PA-6 | 500715-03-7 | 99.3% | 492.61 | 10 MG

Supplier: Medchemexpress LLC HY11254410MG
IK1 inhibitor PA-6, a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. It elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. This product has the potential to treat atrial fibrillation and arrhythmia.
- It is a selective and potent IK1 inhibitor.
- It has IC50 values of 12-15 nM for human and mouse KIR2.x currents.
- It elevates KIR2.1 protein expression.
- It induces intracellular KIR2.1 accumulation.
- It has the potential to treat atrial fibrillation and arrhythmia.
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