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Medchemexpress LLC IK1 inhibitor PA-6 | 500715-03-7 | 99.3% | 492.61 | 50 MG
Supplier: Medchemexpress LLC HY11254450MG
IK1 inhibitor PA-6, a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor. It has IC50 values of 12-15 nM for human and mouse KIR2.x currents and elevates KIR2.1 protein expression, inducing intracellular KIR2.1 accumulation. This inhibitor has the potential to treat atrial fibrillation and arrhythmia.
- Selective and potent IK1 inhibitor
- IC50 values of 12-15 nM for human and mouse KIR2.x currents
- Elevates KIR2.1 protein expression
- Induces intracellular KIR2.1 accumulation
- Potential to treat atrial fibrillation
- Potential to treat arrhythmia
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