Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000347944

Medchemexpress LLC Ikk 16 (hydrochloride) | 1186195-62-9 | 99.9% | 520.09 | 25 MG
SDP

Catalog No. 5000347944
Encompass_Preferred

IKK 16 hydrochloride is an orally active IKK inhibitor. It also acts as a pan-PKD inhibitor and an ABCB1 inhibitor. This compound protects against LPS-induced multiple organ dysfunction, restores renal function, and alleviates fibrosis in acute kidney injury. It further attenuates cardiac dysfunction associated with polymicrobial sepsis in mice with type 2 diabetes mellitus (T2DM) by inhibiting the NF-κB pathway.

  • Acts as an orally active IKK inhibitor
  • Functions as a pan-PKD inhibitor
  • Inhibits ABCB1
  • Protects against LPS-induced multiple organ dysfunction
  • Restores renal function and alleviates fibrosis in acute kidney injury
  • Attenuates cardiac dysfunction associated with polymicrobial sepsis in mice with type 2 diabetes mellitus
  • Inhibits IκB degradation and TNFα-stimulated expression in HUVEC cells
  • Inhibits phosphorylation in specific LRRK2 cells

Catalog No. 50-003-47944 Supplier Medchemexpress LLC Supplier No. 25MGHY13687A
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

IKK 16 hydrochloride is an orally active IKK inhibitor. It also acts as a pan-PKD inhibitor and an ABCB1 inhibitor. This compound protects against LPS-induced multiple organ dysfunction, restores renal function, and alleviates fibrosis in acute kidney injury. It further attenuates cardiac dysfunction associated with polymicrobial sepsis in mice with type 2 diabetes mellitus (T2DM) by inhibiting the NF-κB pathway.

  • Acts as an orally active IKK inhibitor
  • Functions as a pan-PKD inhibitor
  • Inhibits ABCB1
  • Protects against LPS-induced multiple organ dysfunction
  • Restores renal function and alleviates fibrosis in acute kidney injury
  • Attenuates cardiac dysfunction associated with polymicrobial sepsis in mice with type 2 diabetes mellitus
  • Inhibits IκB degradation and TNFα-stimulated expression in HUVEC cells
  • Inhibits phosphorylation in specific LRRK2 cells

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.