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Medchemexpress LLC IKK alpha + IKK beta Antibody (YA349) | 87 kDa | 10 UL
Supplier: Medchemexpress LLC HYP8041410UL
IKKβ protein is a serine kinase crucial for the NF-kappa-B signaling pathway, activated by various stimuli including inflammatory cytokines and cellular stresses. As part of the canonical IKK complex, it mediates the conventional NF-kappa-B activation by phosphorylating inhibitors, leading to their degradation and allowing NF-kappa-B to activate gene transcription for immune response, growth control, and protection against apoptosis. IKKβ also phosphorylates other signaling components, regulating canonical IKKs and influencing diverse cellular processes.
- Rabbit-derived and non-conjugated IgG monoclonal antibody
- Targets IKK alpha + IKK beta
- Reactive with human and mouse samples
- Protein A affinity purified
- Predicted and observed molecular weight: 87 kDa
- Applications include WB, ICC/IF, IP
- Store at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Shipped with blue ice
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