Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Enzo Life Sciences IKK NBD peptide (0.5mg)
Supplier: Enzo Life Sciences BMLP6070500
The peptide consists of two domains - an antennapedia homeodomain that confers cell permeability and the T735 to E745 region of IKKβ which is the NEMO binding domain (NBD). It is a selective inhibitor of NFκB activation. Blocks interaction of NEMO (an IKB complex regulatory protein) with the IκB kinase complex. The peptide (100 µM) inhibits E-selectin expression in human umbilical vein endothelial cells treated with TNFα and inhibits LPS-induced nitric acid release from a macrophage cell line In an experimental mouse model of acute inflammation, IKK-NBD peptide (topically applied) inhibited PMA induced ear inflammation. Sold under license from Vanderbilt University Purity: ≥95% (HPLC). Solubility: Soluble in DMSO (20mM). Note: This peptide will precipitate when added to tissue culture medium, even to 100µM. However, enough will remain in solution to enter many cell types. Long Term Storage: -20°C.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?