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Genscript Corporation Antibody Protein Proteins Proteins 10 UG 1/EA
Supplier: Genscript Corporation Z0321110
Interleukin-12 (IL-12) also known as NKSF TCMF CLMF and TSF is a heterodimeric cytokine composed of p35 and p40 subunits. It is produced by monocytes macrophages B cells and dendritic cells in response to bacterial lipopolysaccharides and intracellular pathogens. IL-12 signals throughtheIL-12 receptor complex which is comprised of IL-12 Rbeta 1 and IL-12 Rbeta 2. IL-12 induces the proliferation and activation of hematopoietic stem cells natural killer cells and T- cells. It is indispensible during the development of Th1 cells leading to the production of IFN-gamma and IL-2.
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