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Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | >99.0% | C27H34N6O2 | 1 ML
Supplier: Medchemexpress LLC HY14169210MM/1ML
IL-17 modulator 4 is a proagent of IL-17 modulator 1, active against IL-17A mediated diseases. This orally active modulator shows promise for the research of conditions including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome. It inhibits IL-17A-mediated signaling pathways by stabilizing the IL-17A dimer and preventing its binding to the IL-17RA receptor.
- Modulates IL-17A protein-protein interaction
- Stabilizes IL-17A dimer conformation
- Prevents IL-17A from binding to IL-17RA receptor
- Inhibits IL-17A-mediated signaling pathways
- Exhibits good pharmacokinetic properties in rat models
- Oral bioavailability of 100% in rat models
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