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Genscript Corporation Antibody Protein Proteins Proteins 1 MG 1/EA
Supplier: Genscript Corporation Z031131
Interleukin-19 (IL-19) is a cytokine belonging to the interleukin family. Structurally IL-19 is grouped into the IL-10 sub-family which also includes IL-20 IL-22 IL-24 and IL-26. In contrast to IL-10 which exists as a homodimer IL-19 is stable and active as a monomer in vivo. IL-19 functions through the receptor complex composed of IL-20 Receptor Alpha and IL-20 ReceptorBeta which is also utilized by IL-20 and IL-24. IL-19 is produced by active monocytes and stimulated synergistically by IL-17 and IL-13. The functions of IL-19 are to promote the development and function of Th2 cells and to enhance the production of Th2 cytokines. IL-19 is implicated in aging vascular disease Type I diabetes and rheumatoid arthritis.
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