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AdipoGen IL-36beta h pAb IN107
SDP

Supplier:  AdipoGen AG25B0032C100

Encompass_Preferred

Polyclonal Antibody. Recognizes human IL-36beta. Does not cross-react with mouse IL-36beta and IL-36gamma. Source Rabbit. Applications ELISA, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. IL-36alpha IL-1F6, IL-36beta IL-1F8 and IL-36gamma IL-1F9 bind to IL-36R IL-1Rrp2 and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Catalog No. 50-256-3187


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