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AdipoGen IL-36gamma (human) Matched Pair Detection Set (1 Set)
SDP

Supplier:  AdipoGen AG46B0010KI01

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Matched Pair Detection Set. Detects human IL-36gamma in cell culture supernatant. Colorimetric assay. Sample Type: Cell Culture Supernatant. Range: 3.9 to 250pg/ml. Sensitivity: 1pg/ml. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Catalog No. 50-205-3341


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