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TARGETMOL CHEMICALS INC IL-4-INHIBITOR-1 5MG

Supplier: TARGETMOL CHEMICALS INC T365275MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. IL-4 inhibitor is an inhibitor of IL-4.1It binds to IL-4 with a Kdvalue of 1.8 uM and inhibits IL-4 activity in a cell-based reporter assay (EC50= 1.81 uM). It is selective for IL-4 over IL-13 (EC50= 18.2 uM). IL-4 inhibitor inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50= 3.1 uM) indicating inhibition of the IL-4-JAK1-STAT6 signaling pathway. purity: 98%
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