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Genscript Corporation Antibody Protein Proteins Proteins 50 UG 1/EA
Supplier: Genscript Corporation Z0315050
Interleukin-4 Receptor also known as IL-4RA and CD124 is a transmembrane glycoprotein belonging to the class I receptor family. It is highly expressed by activated T-cells. IL-4RA couples with gamma chain to form the type I receptor for IL-4. The extracellular domain of IL-4RA binds to IL-4 and antagonizes its activity. IL-4RA plays an important role in Th2 cell differentiation Ig class switching and alternative macrophage activation. It has also been implicated in allergic inflammation tumor progression and atherogenesis.
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