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Genscript Corporation Antibody Protein Proteins Proteins 5 UG 1/EA
Supplier: Genscript Corporation Z031895
Interleukin-6 (IL-6) also known as BSF-2 CDF and IFNB2 is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells macrophages monocytes endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130 inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production myeloma and plasmacytoma growth and nerve cell differentiation. It also acts as a myokine produced by muscle cells in response to muscle contraction and released into the blood stream to help break down fats and improve insulin resistance.
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