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CPC Scientific Ac-Arg-Arg-Trp-Trp-Cys-Arg-NH2 (trifluoroacetate salt) 5MG
Supplier: CPC Scientific ITLK002A
Antileukinate, Ac-RRWWCR-amide, inhibits the specific binding of 125I-labeled IL-8 to neutrophils with an apparent Ki = 10 ?M. The hexapeptide also significantly suppresses neutrophil chemotaxis induced by 10 nM IL-8 at a concentration of 50 ?M. The inhibition is specific for IL-8.ONE-LETTER SEQUENCE: Ac-RRWWCR-NH2MOLECULAR FORMULA: C45H66N18O7S1MOLECULAR WEIGHT:1003.2STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [138559-60-1], RESEARCH AREA: ImmunomodulationREFERENCES: S.Hayashi et al., J. Immunol., 154, 814 (1995); Y.Fukuno et al., Cytokine, 22, 116 (2003); X.Lin et al., Am. J. Physiol. Lung Cell. Mol. Physiol., 289, L583 (2005);
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