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AdipoGen anti-IL-1R2 (mouse), mAb (rec.) (Praxy-1-1) (100 µg)
Supplier: AdipoGen AG27B0011C100
Recombinant Antibody. Recognizes mouse IL-1R2. Species cross-reactivity: Mouse. Clone: Praxy-1-1. Isotype: Mouse IgG2blambda. Applications: ELISA, FACS. Host: Purified from HEK 293 cell culture supernatant. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammatory actions of IL-1alpha and beta depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.
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