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CPC Scientific H-Ile-Met-Gln-Val-Pro-Phe-Ser-Val-OH (trifluoroacetate salt) 1MG
Supplier: CPC Scientific CANS004A
Peptide that contains modified sequence of the gp 100 epitope gp(209-217), in which a methionine replaced the natural threonine at position 2. This peptide also binds to the HLA-A2 molecule with greater affinity than the unmodified peptide and has exhibited a good ability to stimulate melonomareactive cytotoxic T lymphocytes (CTLs) in vitro when used for sensitization of peripheral blood mononuclear cells. This synthetic peptide holds promise for the development of novel cancer immunotherapies.ONE-LETTER SEQUENCE: IMQVPFSVMOLECULAR FORMULA: C43H69N9O11S1MOLECULAR WEIGHT:920.13STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [255710-51-1], RESEARCH AREA: CancerREFERENCES: S.A. Rosenberg et al., Nature Med., 4, 321 (1998)
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