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Selleck Chemical LLC Ilginatinib hydrochloride E4630-25MG
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Catalog No. 5000039087
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Ilginatinib hydrochloride (NS-018 hydrochloride) is a potent small-molecule inhibitor of JAK2 that is competitive with adenosine triphosphate (ATP) which exhibits 30 50-fold greater selectivity for JAK2 over other Jak-family kinases such as JAK1 JAK3 and TYK2 It inhibits JAK2 JAK1 JAK3 and TYK2 with IC50 of 0 72 nM 33 nM 39 nM and 22 nM respectively It also showed potent inhibition of Src-family kinases SRC and FYN It can be used in research of myeloproliferative neoplasms

Catalog No. 50-000-39087 Supplier Selleck Chemical LLC Supplier No. E463025MG
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Ilginatinib hydrochloride (NS-018 hydrochloride) is a potent small-molecule inhibitor of JAK2 that is competitive with adenosine triphosphate (ATP) which exhibits 30 50-fold greater selectivity for JAK2 over other Jak-family kinases such as JAK1 JAK3 and TYK2 It inhibits JAK2 JAK1 JAK3 and TYK2 with IC50 of 0 72 nM 33 nM 39 nM and 22 nM respectively It also showed potent inhibition of Src-family kinases SRC and FYN It can be used in research of myeloproliferative neoplasms

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