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Medchemexpress LLC Ilginatinib hydrochloride | 1239358-85-0 | 98.9% | 425.89 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY19631B

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Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable JAK2 inhibitor. It demonstrates significant selectivity for JAK2 over JAK1, JAK3, and Tyk2. This compound is intended for research use only.

  • Highly active and orally bioavailable JAK2 inhibitor.
  • Exhibits selectivity for JAK2 over JAK1, JAK3, and Tyk2.
  • Potently prolongs survival and reduces splenomegaly in mouse models of myeloproliferative neoplasms.
  • Suppresses colony-forming unit-granulocyte/macrophage (CFU-GM) formation from myelodysplastic syndrome (MDS)-derived bone marrow mononuclear cells.

Catalog No. 50-004-02227


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