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Medchemexpress LLC Imatinib Mesylate | 220127-57-1 | 99.9% | C30H35N7O4S | 5 G
SDP

Catalog No. 5000358366
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Imatinib Mesylate is an orally active tyrosine kinase inhibitor that targets c-Kit, Bcr-Abl, and PDGFR (IC50 ≈ 100 nM). It is intended for research use only, serving as a laboratory chemical and for the manufacture of substances.

  • Inhibits c-Kit autophosphorylation, MAPK, and Akt activation.
  • Effective against Bcr-Abl, Kit, and PDGFR.
  • Multi-target inhibitor for various Abl and Kit kinases.
  • Does not inhibit Src family, c-Fms, Flt3, or EGFR kinases.
  • Inhibits tyrosine phosphorylation and cell growth in specific cell lines.
  • Demonstrates antileukemic activity in CML and Ph+ ALL.
  • Reduces lung injury in rat ischemia/reperfusion injury models.
  • Stable under recommended storage conditions.

Catalog No. 50-003-58366 Supplier Medchemexpress LLC Supplier No. HY509465G
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Imatinib Mesylate is an orally active tyrosine kinase inhibitor that targets c-Kit, Bcr-Abl, and PDGFR (IC50 ≈ 100 nM). It is intended for research use only, serving as a laboratory chemical and for the manufacture of substances.

  • Inhibits c-Kit autophosphorylation, MAPK, and Akt activation.
  • Effective against Bcr-Abl, Kit, and PDGFR.
  • Multi-target inhibitor for various Abl and Kit kinases.
  • Does not inhibit Src family, c-Fms, Flt3, or EGFR kinases.
  • Inhibits tyrosine phosphorylation and cell growth in specific cell lines.
  • Demonstrates antileukemic activity in CML and Ph+ ALL.
  • Reduces lung injury in rat ischemia/reperfusion injury models.
  • Stable under recommended storage conditions.

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