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Cayman Chemical ImepIphydrobromIde 10mg
SDP

Supplier:  Cayman Chemical 2951810 MG

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A histamine H3 receptor agonist (KI = 0.4 nM in SK-N-MC cell membranes expressing the human receptor); selective for histamine H3 over H1 and H2 receptors in CHO cell membranes expressing the guinea pig and human receptors, respectively (Kis = >16 μM for both) but also agonizes H4 receptors (KI = 9 nM in SK-N-MC cell membranes expressing the human receptor); decreases hypothalamic histamine release in anesthetized rats at 5 mg/kg; decreases flinching in the formalin test in rats at 5 and 30 mg/kg and inhibits formalin-induced paw edema at 30 mg/kg

Catalog No. 50-298-9212


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