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Cayman Chemical ImIdaprIlhydrochlorIde 50mg

Supplier: Cayman Chemical 1885450 MG
A prodrug form of imidaprilat; inhibits swine renal cortex ACE activity in vitro (IC50 = 9.9 µM); inhibits the angiotensin I-induced pressor response in normotensive rats; decreases blood pressure in spontaneously hypertensive and 2K-1C renal hypertensive rats at 2 mg/kg; decreases stroke incidence and increases survival in stroke-prone spontaneously hypertensive rats fed a high-salt diet; reduces urinary albumin excretion in a mouse model of streptozotocin-induced diabetes at 5 mg/kg
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