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Apexbio Technology LLC IMIDAZOLE-KETONE-ERASTIN-5MG
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Catalog No. 5000567528
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Imidazole ketone erastin (CAS No 1801530-11-9) is a novel compound primarily used in the field of cancer research Originating from studies on ferroptosis a form of regulated cell death this compound targets the cystine/glutamate antiporter system Xc- inhibiting cystine import and leading to glutathione depletion This results in the accumulation of lipid peroxides ultimately causing cell death in certain cancer cells It has demonstrated activity in the nanomolar to low micromolar range making it a potent agent in in vitro studies Typical applications include cell-based assays to explore its effects on cancer cell viability as well as in vivo animal studies for evaluating its therapeutic potential It is also used in high-throughput drug screening to identify novel anticancer agents Experimental concentrations typically depend on the specific research design allowing for flexibility in its application across various experimental models

Catalog No. 50-005-67528 Supplier Apexbio Technology LLC Supplier No. C84325
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Imidazole ketone erastin (CAS No 1801530-11-9) is a novel compound primarily used in the field of cancer research Originating from studies on ferroptosis a form of regulated cell death this compound targets the cystine/glutamate antiporter system Xc- inhibiting cystine import and leading to glutathione depletion This results in the accumulation of lipid peroxides ultimately causing cell death in certain cancer cells It has demonstrated activity in the nanomolar to low micromolar range making it a potent agent in in vitro studies Typical applications include cell-based assays to explore its effects on cancer cell viability as well as in vivo animal studies for evaluating its therapeutic potential It is also used in high-throughput drug screening to identify novel anticancer agents Experimental concentrations typically depend on the specific research design allowing for flexibility in its application across various experimental models

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