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Medchemexpress LLC Imipramine-d6 | 65100-45-0 | 500 UG
Supplier: Medchemexpress LLC HYB1490AS500UG
Imipramine-d6 is a deuterium-labeled Imipramine hydrochloride. Imipramine is an orally active tertiary amine tricyclic antidepressant, which acts as a Fascin1 inhibitor with antitumor activities and inhibits serotonin transporter with an IC50 value of 32 nM. It stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis, exhibiting neuroprotective and immunomodulatory effects.
- Used as a tracer for quantitation during drug development.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- May affect the pharmacokinetic and metabolic profiles of drugs due to deuteration.
- Fascin1 inhibitor with antitumor activities.
- Inhibits serotonin transporter (IC50 value of 32 nM).
- Stimulates U-87MG glioma cells autophagy.
- Induces HL-60 cell apoptosis.
- Shows neuroprotective effects.
- Exhibits immunomodulatory effects.
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