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Apexbio Technology LLC Imiquimod 99011-02-6 100mg
Supplier: Apexbio Technology LLC A5161100
Imiquimod (CAS 99011-02-6) is a small-molecule agonist targeting Toll-like receptor 7 (TLR7) It is designed to activate TLR7 thereby modulating innate immune responses Imiquimod exerts its biological activity primarily through induction of cytokines such as interferon-gamma and interleukin-12 while suppressing IL-4 and IL-5 thus affecting cellular immunity In in vitro studies imiquimod demonstrates TLR7 activation with an EC50 of approximately 2 1 M and exhibits an anti-proliferative effect mediated by opioid growth factor (OGF) with an IC50 of 2 M Based on these pharmacological properties imiquimod holds research potential in cancer inflammatory diseases and dermatologic conditions including basal cell carcinoma superficial squamous cell carcinoma actinic keratosis and external genital warts
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