Thermo Scientific™ ImmunoCAP™ Fish, Shellfish and Mollusk Allergens

Catalog No.	Quantity	Code	Common Name
14-528-310P	10 Tests	Rf346	Abalone
14-415-901P	16 Tests	f3	Fish (cod)
14-418-001P	16 Tests	f23	Crab
14-418-101P	16 Tests	f24	Shrimp
14-421-301P	16 Tests	f37	Blue mussel
14-421-401P	16 Tests	f40	Tuna
14-421-501P	16 Tests	f41	Salmon
14-429-201P	10 Tests	f80	Lobster
14-443-401P	16 Tests	f254	Plaice
14-445-401P	16 Tests	f50	Chub mackerel
14-446-201P	16 Tests	f58	Pacific squid
14-446-301P	16 Tests	f59	Octopus
14-446-501P	16 Tests	f61	Sardine, Japanese Pilchard
14-446-401P	16 Tests	f60	Jack mackerel, Scad
14-481-901P	10 Tests	f204	Trout
14-482-001P	10 Tests	f207	Clam
14-483-701P	10 Tests	f205	Herring
14-484-201P	10 Tests	f290	Oyster
14-489-501P	10 Tests	f338	Scallop
14-493-110P	10 Tests	Rf381	Red snapper
14-492-810P	10 Tests	Rf147	Gulf flounder
14-493-210P	10 Tests	Rf384	Whitefish (Inconnu)
14-493-010P	10 Tests	Rf369	Cat fish
14-493-710P	10 Tests	Rf414	Tilapia
14-493-910P	10 Tests	Rf42	Haddock
14-493-810P	10 Tests	Rf415	Walleye pike
14-493-610P	10 Tests	Rf413	Pollock
14-501-910P	10 Tests	Rf206	Mackerel
14-514-210P	10 Tests	Rf258	Squid
14-515-910P	10 Tests	Rf304	Langust (spiny lobster)
14-515-810P	10 Tests	Rf303	Halibut
14-519-410P	10 Tests	Rf307	Hake
14-519-510P	10 Tests	Rf308	Sardine (Pilchard)
14-520-410P	10 Tests	Rf311	Megrim
14-520-510P	10 Tests	Rf312	Swordfish
14-521-010P	10 Tests	Rf314	Snail
14-520-910P	10 Tests	Rf313	Anchovy
14-521-910P	10 Tests	Rf320	Crayfish
14-525-610P	10 Tests	Rf337	Sole

Catalog No. 14-528-310P Supplier Thermo Scientific™ Supplier No. 14528310

Description

Measure specifc IgE antibodies using ImmunoCAP™ allergens, an essential tool to aid in the diagnosis of allergic conditions.

Quantify specific IgE antibodies with ImmunoCAP™ Fish, Shellfish and Mollusk Allergens, essential tools to aid in the diagnosis of allergic conditions. IgE antibodies appear in human serum and plasma as a result of sensitization to a specific allergen. Measurement of circulating IgE antibodies provides an objective assessment of sensitization to an allergen. In general, low IgE antibody levels indicate a low probability of allergic disease, whereas high antibody levels to an allergen show a higher correlation with an allergic disease.

ImmunoCAP Specific IgE offers the laboratory:

• Truly quantitative measuring range from 0.1 to 100 kUA/L
• Intra-assay CV (%) comparable to routine clinical chemistry immunoassays
• Excellent consistency over time, and between countries, systems, labs and persons

Expected test values
ImmunoCAP Specific IgE detects IgE antibodies in the range 0.1 to 100 kUA /l, where A represents allergen-specific antibodies. The result is reported quantitatively. In clinical practice, 0.35 kUA /l has commonly been used as a cut-off. A large number of studies have been performed to evaluate the clinical performance of ImmunoCAP Specific IgE tests in allergy diagnosis. Clinical performance is expressed as sensitivity, ranging from 84 to 95%, and specificity, ranging from 85 to 94%. Sensitivity and specificity were reported from multi-center studies including several hundred patients tested for a range of different allergens.

• Specimen collection and preparation
• Use serum and plasma (EDTA or heparin) samples from venous or capillary blood
• Collect blood samples using standard procedures
• Keep specimens at room temperature (RT) for shipping purposes only
• Store at 2–8°C up to one week, otherwise store at –20°C
• Avoid repeated freezing and thawing

Note: Blood samples for testing ImmunoCAP drugs and venom should be collected during or close to the event, preferably not later than 6 months after exposure. If the test result is negative and an IgE-mediated reaction is still strongly suspected, it is advisable to draw a new sample and repeat the test at 5 to 6 weeks.

The presence of specific IgE antibodies is useful to identify the allergens that elicit symptoms and signs of allergy in patients with respiratory allergic diseases including asthma, food allergy, and anaphylactic sensitivity.

Knowing IgE antibody levels provides guidance to clinicians to:

• Identify offending allergens
• Tailor advice to individual patients
• Indicate development of tolerance (food allergy, specific immunotherapy)
• Inform optimized individual medical treatment plans
• Refer to specialists appropriately
• Evaluate whether or not specific immunotherapy is an option

Specific IgE testing also aids in the identification of patients at risk of:

• The allergy march – a progression of skin symptoms to respiratory symptoms
• Severe symptoms including asthma exacerbations – a progression of mild symptoms to severe symptoms
• Progression of recurrent symptoms to persistent symptoms

As in all diagnostic testing, a definitive clinical diagnosis should be made by the clinician after evaluation of all clinical and laboratory findings.

Specifications

• Scientific Name: Haliotis spp.
• Regulatory Status: ASR
• Code Type: Fish, Shellfish, and Mollusk
• Common Name: Abalone
• Quantity: 10 Tests
• Code: Rf346